Medohar for Weight Loss: An Overview

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Introduction to Medo-roga (Obesity)

Cause: Obesity is a condition in which there is an excess amount of body fat. Excess intake of carbohydrates and fats is linked to the incidence of obesity.

There is an imbalance between energy intake and utilisation. Obesity is commonly encountered in middle age group. Other factors linked to obesity include genetics, endocrine disorders like hypothyroidism, or malfunctioning of the adrenal glands.

Signs and symptoms: An obese patient is at maximum risk of developing cardiovascular and endocrinal diseases. Hyperlipidemia (elevated levels of blood cholesterol and triglycerides); hypertension, angina pectoris and diabetes mellitus are common in majority of the patients.

In addition hernia, varicose veins, impotency, and osteoarthritis may be encountered.

Remedies: Guggul is an ideal drug in dealing with obesity and complications. Medohara-guggul, two tablets twice a day after meals is recommended by Ayurveda as a standard treatment of obesity. It should be consumed for three to six months to have an apparent effect.

Raw guggul should not be used as it can lead to gastritis and mouth ulcers. Ladies having history of irregular bleeding should avoid guggul based preparations.

Trina-panchmula-quatha, two tablespoonfuls (30 ml), twice a day, is recommended by Charaka-Samhita for treating obesity.

Precautions and diet: The main aim of treatment is to reduce intake of excess of carbohydrates and fats. The diet should include plenty of green leafy vegetables and fruits. Vitamin A and C are good for obese patients.

Fried foods should be avoided at all costs. Regular exercise under supervision of an instructor is helpful in reducing complications of obesity

  1. Trade name of the herbal medicinal product:

         Medohar

  1. Qualitative and quantitative composition:

               Each Medohar capsule contains following ingredients:

Guggulu (Commiphora mukul)

Trivrit (Operculina turpethum)

Ras Sindur (Red Sulphide of Mercury)

Abhrak Bhasam [Mica (Calcined)]

Tamra Bhasam [Copper (calcined)]

Loh Bhasam [Iron (Calcined)]

Shilajit (Asphaltum punjabianum/Mineral Pitch)

Chitrak Mula (Plumbago zeylenica)

 

  1. Pharmaceutical form:

Capsule

  1. Clinical particulars

4.1: Therapeutic indications

Obesity and weight management

4.2: Posology (dose) and method of administration

1-2 capsules twice-day by oral route.

4.3: Contraindications

Medohar is safe within prescribed dose. It is strongly recommended that product should be taken under strict medical supervision.

4.4: Special warning and special precautions for use

Dehydration

4.5: Interactions with other medicinal products and other forms of interaction

Not established

4.6: Pregnancy and lactation

Contraindicated

4.7: Effects on ability to drive and use machines

Not established.

4.8: Undesirable effects

Not reported.

4.9: Overdose:

Not reported.

  1. Pharmacological properties

The herbs present in Medohar capsules have been used in treatment of obesity in India from centuries.

Guggulu (Commiphora mukul)

  • Medohara-guggul, two tablets twice a day after meals is recommended by Ayurveda as a standard treatment of obesity.
  • In a study the pharmacological effects of mukal were compared with clofibrate. Ether extract of C. mukul (1.5 gms/day) was given to 41 patients. On the other hand clofibrate (92 gms/day) was prescribed to 10 patients. It was concluded that both the drugs were equally effective in controlling serum cholesterol and triglycerides. Incidence of reported side-effects was less with C. mukul group.
  • Fifty patients with a history of coronary artery disease, hyperlipidemia and obesity were treated with daily dose of 10-15 rams of mukul for three months. After completion of the study, 25 per cent reduction in serum cholesterol and 30 per cent reduction in serum triglyceride were observed.
  • A standardisation extract of mukul is based on 2.5 per cent of guggulsterones E and Z is efficacious in the treatment of obesity.

Tamra Bhasam (Incinerated Copper or Copper calyx)

  • Tamra Bhasma is an Ayurvedic medicine, prepared from Copper. It is used in Ayurvedic treatment of skin diseases, obesity, piles, and asthma.
  • The hyperlipidemia was induced by feeding high fat diet in Wistar strain albino rats. The parameters including body weight, weight of various organs, serum lipid profile and histopathology of liver, kidney, heart and aorta were studied. Tamra Bhasma prepared from purified Tamra is having significant anti-hyperlipidemic activity, while unpurified Tamra Bhasma is devoid of such effects.

Shilajit (Asphaltum punjabianum/Mineral Pitch)

  • Shilajit is obtained as exudates from steep rocks. These exudates contain 50 % pure shilajit and rests are impurities.
  • Shilajit when administered internally keeping in mind, disease, dose, vehicle and contraindications can cure all diseases.
  • Purified shilajit is used in the treatment of diabetes, fevers, anaemia, loss of appetite, colic, obesity, abdominal diseases, spleen diseases, angina pectoris and skin diseases.
  • In the present study, 66 patients of obesity were treated with Shilajatu processed with Agnimantha. After completion of therapy, 5.09 ± 0.24 kg and 2.06 ± 0.10 kg/m (2) reduction of body weight and body mass index respectively were noted. The result was found to be statistically highly significant (P<0.001).

5.1: Pharmacodynamic properties

Unknown

5.2: Pharmacokinetic properties

Unknown

5.3: Preclinical safety data

Ingredients used in Medohar formula have a long history of safe traditional use in India.

  1. Pharmaceutical particulars:

6.1: List of excipients

NA

6.2: Incompatibilities

Not known.

6.3: Shelf life

Best for three years if stored under proper conditions

6.4: Special precautions of storage

Store blow 25 degree C and in the original container.

6.5: Nature and contents of container

Vegetarian capsule shell made from plant cellulose containing active moiety.

6.6.: Instructions for use and handling and disposal

Avoid exposure to sunlight and moisture as it may alter the chemical composition of the ingredients.

References

Jagtap CY, Ashok BK, Patgiri BJ, Prajapati PK, Ravishankar B. Comparative anti-hyperlipidemic activity of Tamra Bhasma (incinerated copper) prepared from Shodhita (purified) and Ashodhita Tamra (raw copper). Indian J Nat Prod Res 2013; 4: 205-11.

Pattonder, Ranjan K, Chandola HM, Vyas SN. Clinical efficacy of Shilajatu (asphaltum) processed with Agnimantha (Clerodendrum phlomidis Linn.) in sthaulya (obesity). AYU 2011; 32:526-31.

Acharya SB et al: Pharmacological Actions of Shilajit. Indian J Exp Biol. 1988 26(10), 775-777.

Vaishwanar I, Kowale CN, Jiddewar GG. Effect of two Ayurvedic drugs Shilajit & Eclinol on changes in liver & serum lipids produced by carbon tetrachloride. Indian J Exp Biol. 1976 Jan; 14(1):57-8.

To get more information on Medohar and to buy this ayurvedic product, please click the link below:

Medohar for Weight Loss

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